@article{Galaz-Araya2025,

title = {Molecular Dynamics Study on the Influence of the CLK Motif on the Structural Stability of Collagen-Like Peptides Adsorbed on Gold Nanosurfaces},

author = {Constanza Galaz-Araya and Pablo Galaz-Davison and Diego Cortés-Arriagada and Ricardo A. Zamora and Horacio Poblete},

doi = {10.1021/acsomega.4c10450},

issn = {2470-1343},

year  = {2025},

date = {2025-03-18},

journal = {ACS Omega},

volume = {10},

number = {10},

pages = {10366--10374},

publisher = {American Chemical Society (ACS)},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Zuñiga-Bustos2024,

title = {Unveiling the Potential of RADA16-I Peptide-Coated Silver Nanoparticles for Biomedical Uses: A Computational Study},

author = {Matias Zuñiga-Bustos and Constanza Galaz-Araya and Horacio Poblete},

doi = {10.1039/d4cp03275f},

issn = {1463-9084},

year  = {2024},

date = {2024-12-10},

urldate = {2024-00-00},

journal = {Phys. Chem. Chem. Phys.},

publisher = {Royal Society of Chemistry (RSC)},

abstract = {<jats:p>Nanomaterials, specifically silver nanoparticles (AgNPs), have demonstrated great potential in biomedical applications due to their unique properties, such as antimicrobial activity and conductivity. One promising strategy to improve their biocompatibility...</jats:p>},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{rosales-rojas_self-organization_2022,

title = {Self-Organization Dynamics of Collagen-like Peptides Crosslinking Is Driven by Rose-Bengal-Mediated Electrostatic Bridges},

author = {Roberto Rosales-Rojas and Matías Zuñiga-Bustos and Francisca Salas-Sepúlveda and Constanza Galaz-Araya and Ricardo A. Zamora and Horacio Poblete},

url = {https://www.mdpi.com/1999-4923/14/6/1148},

doi = {10.3390/pharmaceutics14061148},

issn = {1999-4923},

year  = {2022},

date = {2022-05-01},

urldate = {2025-01-02},

journal = {Pharmaceutics},

volume = {14},

number = {6},

pages = {1148},

abstract = {The present work focuses on the computational study of the structural micro-organization of hydrogels based on collagen-like peptides (CLPs) in complex with Rose Bengal (RB). In previous studies, these hydrogels computationally and experimentally demonstrated that when RB was activated by green light, it could generate forms of stable crosslinked structures capable of regenerating biological tissues such as the skin and cornea. Here, we focus on the structural and atomic interactions of two collagen-like peptides (collagen-like peptide I (CLPI), and collagen-like peptide II, (CLPII)) in the presence and absence of RB, highlighting the acquired three-dimensional organization and going deep into the stabilization effect caused by the dye. Our results suggest that the dye could generate a ternary ground-state complex between collagen-like peptide fibers, specifically with positively charged amino acids (Lys in CLPI and Arg in CLPII), thus stabilizing ordered three-dimensional structures. The discoveries generated in this study provide the structural and atomic bases for the subsequent rational development of new synthetic peptides with improved characteristics for applications in the regeneration of biological tissues during photochemical tissue bonding therapies.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{goel_nanoparticle_2019,

title = {Nanoparticle Concentration vs Surface Area in the Interaction of Thiol-Containing Molecules: Toward a Rational Nanoarchitectural Design of Hybrid Materials},

author = {Keshav Goel and Matias Zuñiga-Bustos and Caitlin Lazurko and Erik Jacques and Constanza Galaz-Araya and Francisco Valenzuela-Henriquez and Natalia L. Pacioni and Jean-François Couture and Horacio Poblete and Emilio I. Alarcon},

url = {https://pubs.acs.org/doi/10.1021/acsami.9b03942},

doi = {10.1021/acsami.9b03942},

issn = {1944-8244, 1944-8252},

year  = {2019},

date = {2019-05-01},

urldate = {2025-01-02},

journal = {ACS Applied Materials & Interfaces},

volume = {11},

number = {19},

pages = {17697–17705},

keywords = {},

pubstate = {published},

tppubtype = {article}

}